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Final program FOR TRANSPORTER WORKSHOP 2022

03 May

Please Register by link:

https://docs.google.com/forms/d/1QEzVLBBXnn-HZb8LWxlRtSLMyrCTFVZWNTeCr9A4–E

The instructions for the workshop will be in ENGLISH.

 Registration fees (Deadline 30th June 2022):

  • Academic rate: 150 € (100 € for registration + 50 € for membership)
  • Standard rate: 300€ (250 € for registration + 50 € for membership)
  • Payment could be done by credit card via the GMP site (http://app.gmp.asso.fr/dons) using “Make a donation”.   If you want to pay by bank transfer, please contact at fabrice.hurbin@sanofi.com.

We are looking forward to having your participation in the workshop.

GMP, France

Final Program V1-Integrated In-vitro_in-silico transporter workshop 6 July 2022

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2022 Joint Meeting (DMDG-GMP-SPS): Registration opening & Call for speakers

26 Apr

You will find attached the preliminary agenda prepared by our joint scientific committee. A more detailed program is available here. The final program is under finalization and will be distributed soon.

For logistical reasons, registrations are made via the DMDG website. You can register by clicking here and benefit from a preferential rate (early bird). An academic rate and free registration for students selected to present a poster are proposed. There are a limited number of free places available for Students who wish to present a poster. These are available on a first-come-first-served basis. We would like to draw your attention to the fact that the registration fees (standard early bird: €990€ and academic: €700) include accommodation for the nights and lunch of 3rd & 4th October and refreshments on 3rd, 4th & 5th.

A call for speakers is launched. If you are interested to speak in one of the sessions, please get in touch with the session chairs. The contact details and a description of the sessions can be found on the draft program. The deadline for speaker abstracts is Friday 27th May. For any hot topics or interesting case studies that don’t fit within the regular sessions, please contact the Free Communications session chairs.

We also take opportunity of this announcement to launch a call for Poster to all participants. If you would like to present a poster, please tick the relevant box on the registration form and send your poster abstract to info@dmdg.org. Deadline for poster abstracts is Friday 29 July.

We are looking forward to meeting you at this 1st joint meeting co-organized with the DMDG and SPS. In the meantime do not hesitate to contact us for any enquiries at contact@gmp.asso.fr

Best regards,

 GMP Board

Preliminary agenda_GMP-DMDG-SPS_Joint meeting October

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GMP Newsletter

25 Jan

The GMP board is delighted to share its newsletter number 9, which you will find attached.

We also take this opportunity to inform you that you are closing the call for applications for the scientific committee one week in advance. The members of the 2022 scientific committee will be communicated to you very soon.

Yours faithfully.

GMP Board

GMP Newsletter 9_English_2022-01

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PBPK webinar on 14 January 2022 (2 to 3 pm CET)

08 Dec

GMP webinar : A Growing Network of Open Science: PBPK modelling of Drug–Drug Interactions with the Open Systems Pharmacology Suite

In this webinar we want to feature Physiologically based pharmacokinetics (PBPK) as important tool in drug development [1], which is usually performed when results from known clinicals scenarios are used to predict unknown scenarios [2]. PBPK modelling represents a subdiscipline of System Pharmacology striving to understand the fate of the drug in body including impact of drug-drug interactions (DDI) and drug-gene interactions (DGI) [3]. Despite its generic relevance for drug applications, only a few verified, freely accessible, modifiable, and comprehensive DDI PBPK models are available. The Open Systems Pharmacology (OSP) community aims to overcome this bottlenecks and to grow PBPK knowledge with an open science approach [4]. OSP offers professional open access and open-source software tools (PK-Sim/MoBi) including qualified CYP3A4 DDI networks. Recently this network has been expanded with a CYP1A2 and CYP2C19 network, which can be applied to investigate drug-drug-gene interactions (DDGI). In his presentation Tobias Kanacher will show you how you can leverage the OSP software platform and the community for your drug development project, with a special focus on DDI.

[1]          J. E. Sager, J. Yu, I. Ragueneau-Majlessi, and N. Isoherranen, “Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model Verification,” Drug Metab. Dispos., vol. 43, no. 11, pp. 1823–1837, Nov. 2015, doi: 10.1124/dmd.115.065920.

[2]          L. Kuepfer et al., “Applied Concepts in PBPK Modeling: How to Build a PBPK/PD Model,” CPT Pharmacomet. Syst Pharmacol, vol. 5, no. 10, pp. 516–531, Oct. 2016, doi: 10.1002/psp4.12134.

[3]          T. Kanacher et al., “A Physiologically-Based Pharmacokinetic (PBPK) Model Network for the Prediction of CYP1A2 and CYP2C19 Drug–Drug–Gene Interactions with Fluvoxamine, Omeprazole, S-mephenytoin, Moclobemide, Tizanidine, Mexiletine, Ethinylestradiol, and Caffeine,” Pharmaceutics, vol. 12, no. 12, Art. no. 12, Dec. 2020, doi: 10.3390/pharmaceutics12121191.

[4]          J. Lippert et al., “Open Systems Pharmacology community – an open access, open source, open science approach to modeling and simulation in pharmaceutical sciences,” CPT Pharmacomet. Syst. Pharmacol., vol. n/a, no. n/a, doi: 10.1002/psp4.12473.

Dr. Tobias Kanacher is a senior consultant in pharmacometrics at Pharmetheus. He is a licensed pharmacist and received his PhD from the University of Tübingen in 2003, for biochemical analysis and characterization of enzymatic regulatory domains as potential drug targets. Before joining Pharmetheus (2019-present), he gathered extensive experience in drug discovery and translational clinical development at Altana Pharma AG (2003-2006), Nycomed (2006-2011), Takeda (2011-2012), Bayer (2012-2017) and for SGS-Exprimo (2017-2019). He has broad experience to advice clinical development teams when and how to apply PBPK modelling for influencing internal and regulatory decisions across different stages of clinical drug development.

invite

 

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GMP 2021 Registration opening

29 Jun

2021 GMP Sponsorship Opportunities_Final – Espace Diderot_20-22 October 2021

You can register directly on our website (annual symposium 2021) according to fees indicated below.  Registrations are already open and thus you can take advantage of early bird fees until 03rd September 2021. This will also allow you to guarantee your registration in the event that a sanitary gauge is imposed on us. As a reminder, fees include coffee breaks, lunch on Thursday and Friday, cocktail on Wednesday evening and the gala dinner on Thursday evening.

Should you be eligible to benefit from the student rate, you must contact us (contact@gmp.asso.fr) to obtain a code which will be delivered when the abstract is accepted (see hereafter).

The holding of the symposium is highly dependent on the evolution of the health crisis. In the case the GMP board is forced to cancel this symposium, all registrants will be fully reimbursed.

Early Bird

(before 03rd September 2021)

Late registration

(after 03rd September 2021)

Standard (Members) 670 € 770 €
Standard (Non-members) 720 € 820 €
Academic (Members) 320 € 370 €
Academic (Non-members) 370 € 420 €
Student with Poster * (Members) 90 € 90 €
Student with Poster * (Non-members) 100 € 100 €

* Number is limited (First registered, First served), academic rate will then apply

 

We also take opportunity of this announcement to launch a call for Poster to all our participants. In addition, students may apply to the Poster Blitz session: the 3 most voted posters will be awarded. Abstracts need to be submitted according to the instructions available on the GMP website before 03rd September 2021.

As part of this symposium, the GMP is setting up grants for students. These grants are intended for students enrolled in a Master 2 or equivalent (pharmacy, medicine, etc.) in 2019/2020, 2020/2021 or 2021/2022. All information can be found on the GMP website.

We are also organizing two workshops for Wednesday, October 20th morning. A workshop on modeling offered by Lixoft and a workshop organized jointly with the STP-PT (Suivi Thérapeutique Pharmacologique & Personnalisation des Traitements) unit of the SFPT (Société Française de Pharmacologie et de Thérapeutique) are on preparation. We will get back to you shortly for more detailed information on these events.

We thank our early sponsors and remind others about sponsorship opportunities for this event. Four sponsorship levels are available here (sponsorship-opportunities). Starting from Silver level, the offers include at least one free registration.

We are looking forward to meeting you at our symposium and have great scientific exchanges. In the meantime do not hesitate to contact us for any enquiries at contact@gmp.asso.fr

Best regards,

GMP Board

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